20-O-Acetylingenol-3-angelate, CAS 82425-35-2

Formulation: A solid

Formal Name: (2Z)-2-methyl-2-butenoic acid, (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-4-[(acetyloxy)methyl]-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester

Purity: ≥95%

Formula Markup: C27H36O7

Formula Weight: 472,6

Shelf life (days): 1460

CAS Number: 82425-35-2

Notes: 20-O-Acetylingenol-3-angelate is a diterpene ester that has been found in E. peplus and a derivative of ingenol-3-angelate (Item No. 16207) that has anticancer activity.{72387,72386} It inhibits the growth of K562, HL-60, KT-1, MCF-7/adr, A549, and NIH3T3 cells when used at a concentration of 12.5 µM. 20-O-Acetylingenol-3-angelate (31.25-500 nM) induces cell cycle arrest at the G2/M phase, apoptosis, and necrosis in K562 cells.

• SKU: CAY39904-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 39904-1
• Package Unit: 1 mg
• Quantity Unit: STK