8RK64, CAS 2705841-52-5

Formulation: A solid

Formal Name: N-[5-(2-azidoacetyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl]-1-cyano-3S-pyrrolidinecarboxamide

Purity: ≥95%

Formula Markup: C14H16N8O2S

Formula Weight: 360,4

Shelf life (days): 1460

CAS Number: 2705841-52-5

Notes: 8RK64 is a covalent inhibitor of ubiquitin C-terminal hydrolase L1 (UCH-L1; IC50 = 0.32 µM) and a click chemistry reagent.{51788} It is selective for UCH-L1 over UCH-L3 and UCH-L5 (IC50s = 216 and >1,000 µM, respectively). 8RK64 has been linked to fluorophores containing alkyne groups via copper(I)-catalyzed azide/alkyne cycloaddition (CuAAC) and used to visualize UCH-L1 activity in cells.

• SKU: CAY41148-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41148-5
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Click Chemistry