Formulation: A solid
Formal Name: 2,6-dimethoxy-4-[(1S,3aR,4S,6aR)-tetrahydro-4-(4-hydroxy-3,5-dimethoxyphenyl)-1H,3H-furo[3,4-c]furan-1-yl]phenyl-β-D-glucopyranoside
Purity: ≥95%
Formula Markup: C28H36O13
Formula Weight: 580,6
Shelf life (days): 1460
CAS Number: 7374-79-0
Notes: Acanthoside B is a lignan that has been found in P. villosa and has diverse biological activities.{68703,68704,68705} It scavenges DPPH (Item No. 14805) and ABTS (Item No. 27317) radicals in cell-free assays (IC50s = 9.9 and 12.7 µM, respectively).{68703} Acanthoside B (20 µM) inhibits LPS-induced nitric oxide (NO) production in RAW 264.7 cells.{68704} In vivo, acanthoside B (20 mg/kg) reverses scopolamine-induced memory impairment, reduces hippocampal malondialdehyde (MDA) levels, and increases hippocampal superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPX) levels in a mouse model of scopolamine-induced amnesia.{68705}
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