Formulation: A solid
Formal Name: (1S,4aS,5R,7S,7aS)-7-(acetyloxy)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methylcyclopenta[c]pyran-1-yl, β-D-glucopyranoside
Purity: ≥98%
Formula Markup: C17H26O11
Formula Weight: 406,4
Shelf life (days): 1460
CAS Number: 6926-14-3
Notes: Acetylharpagide is an iridoid glycoside that has been found in A. decumbens and has diverse biological activities.{59103,69693,69694} It reduces the proliferation of A431 skin cancer cells (IC50 = 310 µM).{59103} Acetylharpagide (0.005% in the drinking water) reduces the number of tumors per mouse and the percentage of mice with tumors in a mouse model of 4-nitroquinolin 1-oxide-induced carcinogenesis.{69693} It decreases carrageenan-induced paw swelling in rats when administered at a dose of 10 mg/kg.{69694} Acetylharpagide (10 mg/kg) reduces blood glucose levels in a mouse model of type I diabetes induced by alloxan (Item No. 9002196).
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