2-Ketoglutaric acid-13C, CAS 108395-15-9

Product Description: 2-Ketoglutaric acid-13C (Alpha-Ketoglutaric acid-13C) is a 13C labeled 2-Ketoglutaric acid (HY-W013636)[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2][3].

Formula: C4 13CH6O5

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246./[2]Huergo LF, et al. The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite. Microbiol Mol Biol Rev. 2015 Dec;79(4):419-35./[3]Gou L, et al. The effect of alpha-ketoglutaric acid on tyrosinase activity and conformation: Kinetics and molecular dynamics simulation study. Int J Biol Macromol. 2017 Dec;105(Pt 3):1654-1662.

CAS Number: 108395-15-9

Molecular Weight: 147.09

Compound Purity: 97.0

Research Area: Others

Solubility: 10 mM in DMSO

Target: Isotope-Labeled Compounds

• SKU: MEXHY-W013636S3-500UG
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W013636S3-500UG
• Green Labware: No
• Package Unit: 500 ug
• Quantity Unit: STK