2-Methylsuccinic acid-d6, CAS 347840-08-8

2-Methylsuccinic acid-d6, CAS 347840-08-8
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MEXHY-W010381S-0
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MedChemExpress

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Product Description: 2-Methylsuccinic acid-d6 is the deuterium labeled 2-Methylsuccinic acid[1]. 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy[2][3].

Formula: C5H2D6O4

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Grosso S, et al. Ethylmalonic encephalopathy: further clinical and neuroradiological characterization. J Neurol. 2002 Oct;249(10):1446-50./[3]Nowaczyk MJ, et al. Ethylmalonic and methylsuccinic aciduria in ethylmalonic encephalopathy arise from abnormal isoleucine metabolism. Metabolism. 1998 Jul47(7):836-9.

CAS Number: 347840-08-8

Molecular Weight: 138.15

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite
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SKU MEXHY-W010381S-0
Manufacturer MedChemExpress
Manufacturer SKU HY-W010381S-0
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