Product Description: 3-Ethylaniline-d5 is the deuterium labeled 3-Ethylaniline (HY-W010482). 3-Ethylaniline is metabolized in vivo to electrophilic intermediates that covalently bind to DNA and that adducts are formed in the DNA of bladder. 3-Ethylaniline can be used for the research of bladder cancer[1][2].
Applications: Cancer-programmed cell death
Formula: C8H6D5N
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. /[2]Paul L Skipper, et al. DNA adduct formation by 2,6-dimethyl-, 3,5-dimethyl-, and 3-ethylaniline in vivo in mice. Chem Res Toxicol. 2006 Aug;19(8):1086-90.
CAS Number: 1643538-19-5
Molecular Weight: 126.21
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Isotope-Labeled Compounds