4-Hydroxyphenylacetic acid-d4

Product Description: 4-Hydroxyphenylacetic acid-d4 is the deuterium labeled 4-Hydroxyphenylacetic acid[1]. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2[2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C8H4D4O3

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Zhao H, et al. 4-Hydroxyphenylacetic Acid Prevents Acute APAP-Induced Liver Injury by Increasing Phase IIand Antioxidant Enzymes in Mice. Front Pharmacol. 2018 Jun 19;9:653.

Molecular Weight: 156.17

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite;Keap1-Nrf2

• SKU: MEXHY-N1902S1-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N1902S1-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK