Product Description: 4-Methylcatechol-d8 is the deuterium labeled 4-Methylcatechol[1]. 4-Methylcatechol, a metabolite of p-toluate, is a substrate as well as a suicide inhibitor of Catechol 2,3-Dioxygenase[2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C7D8O2
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Okuta A, et al. Construction of chimeric catechol 2,3-dioxygenase exhibiting improved activity against the suicide inhibitor 4-methylcatechol. Appl Environ Microbiol. 2004 Mar;70(3):1804-10.
CAS Number: 1219803-18-5
Molecular Weight: 132.19
Research Area: Others
Solubility: 10 mM in DMSO
Target: Endogenous Metabolite