(4-NH2)-Exatecan-d5

Product Description: (4-NH2)-Exatecan-d5 is a deuterated labeled (4-NH2)-Exatecan[1]. (4-NH2)-Exatecan (compound A), a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs)[2].

Formula: C23H16D5N3O4

References: [1]Howard PW, et, al. Compounds and conjugates thereof. US20200306243A1./[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 408.46

Compound Purity: 98.62

Research Area: Cancer

Solubility: DMSO : 33.33 mg/mL (ultrasonic)

Target: ADC Cytotoxin;Isotope-Labeled Compounds;Topoisomerase

• SKU: MEXHY-145397S-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-145397S-5
• Package Unit: 5 mg
• Quantity Unit: STK