5-Hydroxymethyluracil-d3, CAS 352438-73-4

Product Description: 5-Hydroxymethyluracil-d3 is the deuterium labeled 5-Hydroxymethyluracil[1]. 5-Hydroxymethyluracil is a product of oxidative DNA damage. 5-Hydroxymethyluracil can be used as a potential epigenetic mark enhancing or inhibiting transcription with bacterial RNA polymerase[2][3].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C5H3D3N2O3

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Djuric Z, et al. Quantitation of 5-(hydroxymethyl)uracil in DNA by gas chromatography with mass spectral detection. Chem Res Toxicol. 1991 Nov-Dec;4(6):687-91./[3]Janoušková M, et al. 5-(Hydroxymethyl)uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase. Chem Commun (Camb). 2017 Dec 12;53(99):13253-13255.

CAS Number: 352438-73-4

Molecular Weight: 145.13

Research Area: Others

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite

• SKU: MEXHY-W004924S-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W004924S-1
• Package Unit: 1 mg
• Quantity Unit: STK