α-Zearalenol-d4, CAS 1778734-73-8

α-Zearalenol-d4, CAS 1778734-73-8
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MEXHY-N6710S-0
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MedChemExpress

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Product Description: α-Zearalenol-d4 is a deuterated labeled α-Zearalenol[1]. α-Zearalenol is a Mycotoxin with high affinity for the estrogen receptors (ER),α-Zearalenol is the derivative of zearalenone (ZEN), causes reproductive disorders in animals, due to its xenoestrogenic effects[2].

Formula: C18H20D4O5

References: [1].Tatay E, et al. Estrogenic activity of zearalenone, α-zearalenol and β-zearalenol assessed using the E-screen assay in MCF-7 cells. Toxicol Mech Methods. 2018 May;28(4):239-242./[2]Marin DE, et al. Cytotoxic and inflammatory effects of individual and combined exposure of HepG2 cells to zearalenone and its metabolites. Naunyn Schmiedebergs Arch Pharmacol. 2019 Aug;392(8):937-947./[3]Nittoli AC, et al. Effects of α-zearalenol on the metabolome of two breast cancer cell lines by 1H-NMR approach. Metabolomics. 2018 Feb 14;14(3):33./[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

CAS Number: 1778734-73-8

Molecular Weight: 324.40

Research Area: Inflammation/Immunology

Target: Estrogen Receptor/ERR;Isotope-Labeled Compounds
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SKU MEXHY-N6710S-0
Manufacturer MedChemExpress
Manufacturer SKU HY-N6710S-0
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