Product Description: Adenosine-13C10 (Adenine riboside-13C10; D-Adenosine-13C10) is 13C-labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
Applications: Metabolism-protein/nucleotide metabolism
Formula: 13C10H13N5O4
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Zhou XT, et al. Inhibition of autophagy enhances adenosine induced apoptosis in human hepatoblastoma HepG2 cells. Oncol Rep. 2019;41(2):829-838./[3]Eltzschig HK. Adenosine: an old drug newly discovered. Anesthesiology. 2009;111(4):904-915./[4]Borea PA, Gessi S, Merighi S, Vincenzi F, Varani K. Pharmacology of Adenosine Receptors: The State of the Art. Physiol Rev. 2018;98(3):1591-1625./[5]Fredholm BB. Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ. 2007;14(7):1315-1323.
CAS Number: 1887761-94-5
Molecular Weight: 277.17
Research Area: Cancer; Metabolic Disease
Solubility: 10 mM in DMSO
Target: Apoptosis;Autophagy;Endogenous Metabolite;Isotope-Labeled Compounds;Nucleoside Antimetabolite/Analog
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