Arotinolol-d5 (hydrochloride), CAS 2514848-16-7

Product Description: Arotinolol-d5 (hydrochloride) is deuterium labeled Arotinolol. Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker[1][2][3]. Arotinolol also shows potency for inhibiting the binding of the radioligand 125I-ICYP to 5HT1B-serotonergic receptor sites. Arotinolol is an antihypertensive agent for the treatment of a variety of cardiovascular pathologies as well as non-cardiovascular diseases[1][2][3].

Formula: C15H17D5ClN3O2S3

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Zhou W, et al. Mechanisms of improved aortic stiffness by arotinolol in spontaneously hypertensive rats.PLoS One. 2014 Feb 12;9(2):e88722./[3]Hiroshi TSUCHIHASHI, et al. Characteristics of 1251-lodocyanopindolol Binding to 8-Adrenergic and Serotonin-1B Receptors of Rat Brain: Selectivity of 19-Adrenergic Agents

CAS Number: 2514848-16-7

Molecular Weight: 413.03

Research Area: Cardiovascular Disease

Target: 5-HT Receptor;Adrenergic Receptor;Isotope-Labeled Compounds

• SKU: MEXHY-W653969-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W653969-0
• Package Unit: Get quote
• Quantity Unit: STK