Benzocaine-d4, CAS 342611-08-9

Product Description: Benzocaine-d4 is the deuterium labeled Benzocaine. Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel, with an IC50 of 0.8 mM tested with a potential of +30 mV.

Formula: C9H7D4NO2

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Wang GK et al. A common local anesthetic receptor for benzocaine and etidocaine in voltage-gated mu1 Na+ channels. Pflugers Arch. 1998 Jan;435(2):293-302./[3]Di Croce D et al. Drug action of benzocaine on the sarcoplasmic reticulum Ca-ATPase from fast-twitch skeletal muscle. Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388(11):1163-70./[4]Davis JA, et al. Benzocaine-induced methemoglobinemia attributed to topical application of the anesthetic in several laboratory animal species. Am J Vet Res. 1993 Aug;54(8):1322-6.

CAS Number: 342611-08-9

Molecular Weight: 169.21

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Isotope-Labeled Compounds;Sodium Channel

• SKU: MEXHY-Y0258S-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-Y0258S-10
• Package Unit: 10 mg
• Quantity Unit: STK