Bictegravir-d5

Product Description: Bictegravir-d5 is deuterated labeled Bictegravir (HY-17605). Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM.

Applications: COVID-19-anti-virus

Formula: C21H13D5F3N3O5

References: [1]Tsiang M, et al. Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile. Antimicrob Agents Chemother. 2016 Nov 21;60(12):7086-7097./[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 454.41

Research Area: Infection

Solubility: 10 mM in DMSO

Target: HIV;HIV Integrase;Isotope-Labeled Compounds

• SKU: MEXHY-17605S1-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-17605S1-0
• Package Unit: Get quote
• Quantity Unit: STK