Product Description: Carbamazepine-d10 is the deuterium labeled Carbamazepine. Carbamazepine (CBZ), a sodium channel blocker, is an anticonvulsant agent[1][2].
Applications: Cancer-programmed cell death
Formula: C15H2D10N2O
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Willow, M. and W.A. Catterall, Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by the anticonvulsant drugs diphenylhydantoin and carbamazepine. Mol Pharmacol, 1982. 22(3): p. 627-35./[3]Okada, M., et al., Biphasic effects of carbamazepine on the dopaminergic system in rat striatum and hippocampus. Epilepsy Res, 1997. 28(2): p. 143-53.
CAS Number: 132183-78-9
Molecular Weight: 246.33
Compound Purity: 99.41
Research Area: Neurological Disease; Cancer
Solubility: DMF : ≥ 25 mg/mL/DMSO : ≥ 25 mg/mL/DMSO:PBS (pH 7.2) (1:1) : ≥ 0.5 mg/mL/Ethanol : ≥ 3 mg/mL
Target: Autophagy;Mitophagy;Sodium Channel
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