Product Description: Cariprazine-d6 is a deuterium labeled Cariprazine. Cariprazine Cariprazine is an antipsychotic agent that exhibits high affinity for the D3 (Ki of 0.085 nM) and D2 (Ki of 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki of 2.6 nM)[1].
Applications: Neuroscience-Neuromodulation
Formula: C21H26D6Cl2N4O
References: [1] Seneca N, et al. Occupancy of dopamine D2 and D3 and serotonin 5-HT1A receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography. Psychopharmacology (Berl). 2011 Dec;218(3):579-8
CAS Number: 1308278-67-2
Molecular Weight: 433.45
Compound Purity: 98.00
Research Area: Neurological Disease
Solubility: DMSO : 33.33 mg/mL (ultrasonic;warming;heat to 160°C)
Target: 5-HT Receptor;Dopamine Receptor