Chlorzoxazone-d3, CAS 1185173-60-7

Product Description: Chlorzoxazone-d3 is the deuterium labeled Chlorzoxazone. Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes.Chlorzoxazone is currently being used as a marker substrate in vitro/vivo studies to quantify cytochrome P450 2E1 (CYP2E1) activity in humans.

Formula: C7HD3ClNO2

References: [1]Yamamura Y, et al. Comprehensive kinetic analysis and influence of reaction components for chlorzoxazone 6-hydroxylation in human liver microsomes with CYP antibodies. Xenobiotica. 2015 Apr;45(4):353-360./[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 1185173-60-7

Molecular Weight: 172.58

Compound Purity: 98.50

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Cytochrome P450

• SKU: MEXHY-B1462S-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B1462S-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK