Cycloguanil-d6 (hydrochloride), CAS 2712364-69-5

Product Description: Cycloguanil-d6 hydrochloride is the deuterium labeled Cycloguanil hydrochloride. Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes[1].

Formula: C11H9D6Cl2N5

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Matthaei J, et al. OCT1 Deficiency Affects Hepatocellular Concentrations and Pharmacokinetics of Cycloguanil, the Active Metabolite of the Antimalarial Drug Proguanil. Clin Pharmacol Ther. 2019 Jan;105(1):190-200.

CAS Number: 2712364-69-5

Molecular Weight: 294.21

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Drug Metabolite;Isotope-Labeled Compounds;Parasite

• SKU: MEXHY-12784AS1-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12784AS1-5
• Package Unit: 5mg
• Quantity Unit: STK