Product Description: Deoxycholic acid-13C is the 13C-labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
Applications: Metabolism-sugar/lipid metabolism
Formula: C23 13CH40O4
References: [1]Somm E, et al. β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue. JCI Insight. 2017 Apr 20;2(8). pii: 91809./[2]Wang X, et al. Acidified bile acids enhance tumor progression and telomerase activity of gastric cancer in micedependent on c-Myc expression. Cancer Med. 2017 Apr;6(4):788-797./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number: 52886-37-0
Molecular Weight: 393.56
Compound Purity: 98.00
Research Area: Metabolic Disease
Solubility: DMSO : ≥ 100 mg/mL
Target: Endogenous Metabolite;G protein-coupled Bile Acid Receptor 1
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