Product Description: Dicloxacillin-13C4 is the 13C labeled Dicloxacillin[1]. Dicloxacillin is a β-lactam antibiotic of the penicillin family. Dicloxacillin against Gram-positive bacteria. Dicloxacillin is active against β-lactamase-producing organisms such as Staphylococcus aureus[2].
Applications: COVID-19-immunoregulation
Formula: C15 13C4H17Cl2N3O5S
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Miranda-Novales G, et al. In vitro activity effects of combinations of cephalothin, dicloxacillin, imipenem, vancomycin and amikacin against methicillin-resistant Staphylococcus spp. strains. Ann Clin Microbiol Antimicrob. 2006 Oct 12;5:25./[3]Anne Sandberg, et al. Intra- and extracellular activities of dicloxacillin against Staphylococcus aureus in vivo and in vitro. Antimicrob Agents Chemother. 2010 Jun54(6):2391-400./[4]John Chu, et al. Discovery of MRSA active antibiotics using primary sequence from the human microbiome. Nat Chem Biol. 2016 Dec12(12):1004-1006.
Molecular Weight: 474.30
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Antibiotic;Bacterial
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