Product Description: Dihydrocapsaicin-d3is the deuterium labeledDihydrocapsaicin(HY-N0361)[1]. Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF, Bax, and Caspase-3 expressions, and increased Bcl-2, Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat[2][3][4].
Formula: C18H26D3NO3
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
CAS Number: 1330261-21-6
Molecular Weight: 310.45
Research Area: Others
Solubility: 10 mM in DMSO
Target: Isotope-Labeled Compounds