Diosmetin-d3, CAS 1189728-54-8

Product Description: Diosmetin-d3 is the deuterium labeled Diosmetin. Diosmetin is a natural flavonoid which inhibits human CYP1A enzyme activity with an IC50 of 40 μM in HepG2 cell.

Formula: C16H9D3O6

References: [1]Liu B, et al. Diosmetin induces apoptosis by upregulating p53 via the TGF-β signal pathway in HepG2 hepatoma cells. Mol Med Rep. 2016 Jul;14(1):159-64./[2]Yu G, et al. Diosmetin ameliorates the severity of cerulein-induced acute pancreatitis in mice by inhibiting the activation of the nuclear factor-κB. Int J Clin Exp Pathol. 2014 Apr 15;7(5):2133-42./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 1189728-54-8

Molecular Weight: 303.28

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Cytochrome P450;Isotope-Labeled Compounds

• SKU: MEXHY-N0125S-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N0125S-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK