Product Description: Exatecan-d3 (DX8951f-d3) mesylate is deuterium-labeled Exatecan (mesylate) (HY-13631A)[1].
Formula: C25H23D3FN3O7S
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Smith K A, et al. Soil and environmental analysis[M]. Marcel Dekker Incorporated, 2000./[3]Fan T W M, et al. Stable isotope-resolved metabolomics and applications for drug development[J]. Pharmacology & therapeutics, 2012, 133(3): 366-391.
Molecular Weight: 534.57
Research Area: Cancer
Target: ADC Cytotoxin;Isotope-Labeled Compounds;Topoisomerase