Frovatriptan-d3 (hydrochloride)

Frovatriptan-d3 (hydrochloride)
SKU
MEXHY-B1658S-0
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MedChemExpress

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Product Description: Frovatriptan-d3 (hydrochloride) is the deuterium labeled Frovatriptan[1]. Frovatriptan is a potent 5-HT1B//D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan is apparently cerebroselective. Frovatriptan is efficacious and even superior in some endpoints also when taken during the headache phase in migraine attacks with aura[2].

Applications: Neuroscience-Neuromodulation

Formula: C14H15D3ClN3O

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Stefan Evers, et al. Efficacy of frovatriptan as compared to other triptans in migraine with aura.

Molecular Weight: 282.78

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: 5-HT Receptor
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SKU MEXHY-B1658S-0
Manufacturer MedChemExpress
Manufacturer SKU HY-B1658S-0
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