Product Description: Glycine-13C2,15N,d2 is the deuterium, 13C and 15N labeled Glycine[1]. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors[2].
Applications: Neuroscience-Neurodegeneration
Formula: 13C2H3D2 15NO2
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Johnson JW, et al. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature. 1987 Feb 5-11;325(6104):529-31.
CAS Number: 1984075-49-1
Molecular Weight: 80.06
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Endogenous Metabolite;iGluR