Glycochenodeoxycholic acid-d7 (sodium)

Product Description: Glycochenodeoxycholic acid-d7 (sodium) is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2].

Formula: C26H35D7NNaO5

References: [1]Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30./[2]Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Molecular Weight: 478.65

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Endogenous Metabolite;Isotope-Labeled Compounds

• SKU: MEXHY-N2334AS-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N2334AS-5
• Green Labware: No
• Package Unit: 5mg
• Quantity Unit: STK