Guanfacine-d2 (hydrochloride), CAS 1398065-88-7

Product Description: Guanfacine-d2 (hydrochloride) is the deuterium labeled Guanfacine hydrochloride. Guanfacine hydrochloride, an anti-hypertensive agent, is a selective α2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over α2B-adrenoceptors[1][2].

Formula: C9H8D2Cl3N3O

References: [1]Wang J, et al. Huperzine a improves chronic inflammation and cognitive decline in rats with cerebral hypoperfusion. J Neurosci Res. 2010 Mar;88(4):807-15./[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 1398065-88-7

Molecular Weight: 284.57

Research Area: Cardiovascular Disease; Endocrinology

Solubility: 10 mM in DMSO

Target: Adrenergic Receptor;Isotope-Labeled Compounds

• SKU: MEXHY-17416S-500UG
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-17416S-500UG
• Package Unit: 500 μg
• Quantity Unit: STK