Hypericin-d10

Product Description: Hypericin-d10 is the deuterium labeled Hypericin. Hypericin is a photosensitive antiviral with anticancer and antidepressant agent derived from Hypericum perforatum. It can inhibit tyrosine kinases with IC50 of 7.5 μM.

Formula: C30H6D10O8

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Agostinis P et al. Hypericin in cancer treatment: more light on the way. Int J Biochem Cell Biol. 2002 Mar;34(3):221-41./[3]Lenard J et al. Photodynamic inactivation of infectivity of human immunodeficiency virus and other enveloped viruses usinghypericin and rose bengal: inhibition of fusion and syncytia formation. Proc Natl Acad Sci U S A. 1993 Jan 1;90(1):158-62./[4]Hwang MS et al. Inhibition of c-erbB-2 expression an activity in human ovarian carcinoma cells by hypericin. Anticancer Res. 2001 Jul-Aug;21(4A):2649-55.

Molecular Weight: 514.50

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Influenza Virus;Isotope-Labeled Compounds

• SKU: MEXHY-N0453S-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N0453S-5
• Green Labware: No
• Package Unit: 5mg
• Quantity Unit: STK