Ixazomib-13C2,15N

Product Description: Ixazomib-13C2,15N is 13C and 15N labeled Ixazomib. Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM)[1].

Formula: C12 13C2H19BCl2N 15NO4

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Friedman JR, et al. Anticancer Activity of Natural and Synthetic Capsaicin Analogs. J Pharmacol Exp Ther. 2018 Mar;364(3):462-473.

Molecular Weight: 364.01

Research Area: Cancer

Target: Autophagy;Isotope-Labeled Compounds;Proteasome

• SKU: MEXHY-W748328-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W748328-0
• Package Unit: Get quote
• Quantity Unit: STK