Kukoamine A-d8 (dihydrochloride)

Product Description: Kukoamine A-d8 (dihydrochloride) is deuterium labeled Kukoamine A. Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (Ki, 1.8 μM), with antihypertensive activity[1].

Applications: COVID-19-immunoregulation

Formula: C28H36D8Cl2N4O6

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Ponasik JA, et al. Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase. Biochem J. 1995 Oct 15;311 ( Pt 2):371-5.

Molecular Weight: 611.63

Research Area: Infection; Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Isotope-Labeled Compounds;Parasite

• SKU: MEXHY-N2392S-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N2392S-5
• Green Labware: No
• Package Unit: 5mg
• Quantity Unit: STK