Product Description: L-Arginine-13C6,d14 hydrochloride ((S)-(+)-Arginine-13C6,d14 hydrochloride) is a deuterated derivative of L-Arginine hydrochloride (HY-N0455A) that is labeled with 13C6. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) serves as a nitrogen donor for the synthesis of nitric oxide and is a vasodilator[1][2][3][4][5].
Formula: 13C6HD14ClN4O2
References: [1]Bakker J, et al. Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002). Crit Care Med. 2004 Jan;32(1):1-12./[2]Tapiero H, et al. I. Arginine. Biomed Pharmacother. 2002 Nov;56(9):439-45./[3]Yamada M, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr;20(4):709-17./[4]Mizunuma T, et al. Effects of injecting excess arginine on rat pancreas. J Nutr. 1984 Mar;114(3):467-71./[5]Siriviriyakul P, et al. Effects of curcumin on oxidative stress, inflammation and apoptosis in L-arginine induced acute pancreatitis in mice. Heliyon. 2019 Aug 27;5(8):e02222.
Molecular Weight: 230.70
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Endogenous Metabolite;Isotope-Labeled Compounds