Product Description: L-Ascorbic acid-13C-1 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen
Applications: Metabolism-sugar/lipid metabolism
Formula: C5 13CH8O6
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Sebastian J Padayatty, et al. Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr. 2003 Feb;22(1):18-35.;Michael T Nelson, et al. Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels
CAS Number: 178101-89-8
Molecular Weight: 177.12
Research Area: Cancer; Metabolic Disease; Neurological Disease
Solubility: 10 mM in DMSO
Target: Apoptosis;Calcium Channel;Endogenous Metabolite;Isotope-Labeled Compounds;Reactive Oxygen Species
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