L-Phenylalanine-15N,d8

Product Description: L-Phenylalanine-15N,d8 is the deuterium and 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca2+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C9H3D8 15NO2

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Molecular Weight: 174.23

Compound Purity: 99.90

Research Area: Metabolic Disease

Solubility: H2O : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Calcium Channel;Endogenous Metabolite;iGluR;Isotope-Labeled Compounds

• SKU: MEXHY-N0215S14-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N0215S14-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK