Ledipasvir-d6 (hydrochloride)

Ledipasvir-d6 (hydrochloride)
SKU
MEXHY-15602AS-0
Packaging Unit
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Manufacturer
MedChemExpress

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Product Description: Ledipasvir-d6 hydrochloride is deuterated labeled Ledipasvir acetone (HY-15602A). Ledipasvir acetone (GS-5885 acetone) is the active ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.

Applications: COVID-19-anti-virus

Formula: C49H49D6ClF2N8O6

References: [1]Link JO, et al. Discovery of ledipasvir (GS-5885): a potent, once-daily oral NS5A inhibitor for the treatment of hepatitis C virus infection. J Med Chem. 2014 Mar 13;57(5):2033-46./[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 931.50

Research Area: Infection

Solubility: 10 mM in DMSO

Target: HCV;Isotope-Labeled Compounds
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SKU MEXHY-15602AS-0
Manufacturer MedChemExpress
Manufacturer SKU HY-15602AS-0
Green Labware No
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