Levocetirizine-d4 (dihydrochloride)

Product Description: Levocetirizine-d4 (dihydrochloride) is the deuterium labeled Levocetirizine. Levocetirizine ((R)-Cetirizine) is a third-generation peripheral H1-receptor antagonist. Levocetirizine is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria[1].

Formula: C21H23D4Cl3N2O3

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Lohar P, et al. Simultaneous bioanalysis and pharmacokinetic interaction study of acebrophylline, levocetirizine and pranlukast in Sprague-Dawley rats. Biomed Chromatogr. 2019 Dec;33(12):e4672.

Molecular Weight: 465.83

Research Area: Inflammation/Immunology; Endocrinology

Solubility: 10 mM in DMSO

Target: Histamine Receptor;Isotope-Labeled Compounds

• SKU: MEXHY-B0814S-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B0814S-5
• Green Labware: No
• Package Unit: 5mg
• Quantity Unit: STK