Product Description: Meglutol-d3 is the deuterium labeled Meglutol[1]. Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol.
Formula: C6H7D3O5
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
CAS Number: 59060-36-5
Molecular Weight: 165.16
Compound Purity: 95.00
Research Area: Cardiovascular Disease
Solubility: 10 mM in DMSO
Target: Autophagy;Endogenous Metabolite;HMG-CoA Reductase (HMGCR)