Metaproterenol-d7 (hemisulfate)

Product Description: Metaproterenol-d7 (hemisulfate) is the deuterium labeled Metaproterenol hemisulfate. Metaproterenol hemisulfate (Orciprenaline hemisulfate) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol hemisulfate also has anti-inflammatory activity[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C11H12D7NO7S

References: [1]Noh H, et al. Beta 2-adrenergic receptor agonists are novel regulators of macrophage activation in diabetic renal and cardiovascular complications. Kidney Int. 2017 Jul;92(1):101-113./[2]Ibrahim FA, et al. Highly sensitive spectrofluorimetric method for rapid determination of orciprenaline in biological fluids and pharmaceuticals. Luminescence. 2019 Feb;34(1):77-83./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Molecular Weight: 267.34

Research Area: Inflammation/Immunology; Cardiovascular Disease; Endocrinology

Solubility: 10 mM in DMSO

Target: Adrenergic Receptor;Isotope-Labeled Compounds

• SKU: MEXHY-B1276S-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B1276S-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK