Methylisothiazolinone-d3 (hydrochloride), CAS 1329509-49-0

Product Description: Methylisothiazolinone-d3 (hydrochloride) is the deuterium labeled Methylisothiazolinone (hydrochloride). Methylisothiazolinone hydrochloride is the constituent of the biocide Kathon CG. Methylisothiazolinone hydrochloride is an isothiazolone derivative widely used as a preservative. Methylisothiazolinone hydrochloride is also a moderate sensitizer and reacts with GSH.

Applications: COVID-19-immunoregulation

Formula: C4H3D3ClNOS

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Aynur O Aptula, et al. From Experiment to Theory: Molecular Orbital Parameters to Interpret the Skin Sensitization Potential of 5-chloro-2-methylisothiazol-3-one and 2-methylisothiazol-3-one. Chem Res Toxicol. 2005 Feb;18(2):324-9./[3]Rubén Alvarez-Sánchez, et al. Covalent Binding of the 13C-labeled Skin Sensitizers 5-chloro-2-methylisothiazol-3-one (MCI) and 2-methylisothiazol-3-one (MI) to a Model Peptide and Glutathione. Bioorg Med Chem Lett. 2004 Jan 19;14(2):365-8.

CAS Number: 1329509-49-0

Molecular Weight: 154.63

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Bacterial;Isotope-Labeled Compounds

• SKU: MEXHY-W010243S-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W010243S-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK