Moclobemide-d8, CAS 2309010-25-9

Product Description: Moclobemide-d8 (Ro111163-d8) is the deuterium labeled Moclobemide. Moclobemide (Ro111163) is a brain-penetrant and reversible monoamine oxidase (MAO-A) inhibitor with an IC50 of 6.061 μM for hMAO-A[1].Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice.

Formula: C13H9D8ClN2O2

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Nafiz Öncü Can, et al. Synthesis of New Hydrazone Derivatives for MAO Enzymes Inhibitory Activity. Molecules. 2017 Aug 20;22(8):1381./[3]Yun-feng Li, et al. Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice. Acta Pharmacol Sin. 2004 Nov;25(11):1408-12.

CAS Number: 2309010-25-9

Molecular Weight: 276.79

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Isotope-Labeled Compounds;Monoamine Oxidase

• SKU: MEXHY-B0534S-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B0534S-5
• Package Unit: 5mg
• Quantity Unit: STK