Product Description: Nerol-d2 is deuterated labeled Octanal (HY-N8015). Octanal is an aromatic aldehyde, with antioxidant and antimicrobial activities. Octanal shows cytotoxicity against Hela cells[1].
Applications: Metabolism-sugar/lipid metabolism
Formula: C10H16D2O
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Tian J, et al. Nerol-induced apoptosis associated with the generation of ROS and Ca<sup>2+</sup> overload in saprotrophic fungus <i>Aspergillus flavus</i>. Appl Microbiol Biotechnol. 2018 Aug;102(15):6659-6672./[3]Tian J, et al. Nerol triggers mitochondrial dysfunction and disruption via elevation of Ca<sup>2+</sup> and ROS in <i>Candida albicans</i>. Int J Biochem Cell Biol. 2017 Apr;85:114-122.
CAS Number: 32637-85-7
Molecular Weight: 156.26
Solubility: 10 mM in DMSO
Target: Apoptosis;Endogenous Metabolite;Fungal;Isotope-Labeled Compounds;Mitochondrial Metabolism;Reactive Oxygen Species