Olsalazine-d3,15N

Product Description: Olsalazine-d3,15N is 15N and deuterated labeled Olsalazine (HY-B0174A). Olsalazine is a potent inhibitor of macrophages chemotaxis to LTB4 with an IC50 value of 0.39 mM, also reduces the synthesis of 5-hydroxyeicosatetraenoic acid (5-HETE), 11-HETE, 12-HETE, and 15-HETE in polymorphonuclear leukocyte (PMNL) and mononuclear cells (MNL). Olsalazine can be used for researching ulcerative colitis. Anti-inflammatory activity[1][2].

Applications: COVID-19-immunoregulation

Formula: C14H7D3N 15NO6

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 306.25

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Antibiotic;Isotope-Labeled Compounds;Leukotriene Receptor

• SKU: MEXHY-B0174AS2-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B0174AS2-0
• Package Unit: Get quote
• Quantity Unit: STK