Oxprenolol-d7 (hydrochloride), CAS 1189649-47-5

Product Description: Oxprenolol-d7 (hydrochloride) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle[1].

Formula: C15H17D7ClNO3

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]T Nagatomo, et al. Binding Characteristics of ³H-dihydroalprenolol to Beta-Adrenoceptors of Rat Heart Treated With Neuraminidase. Jpn J Pharmacol. 1983 Aug;33(4):851-7./[3]A S Manning, et al. Abrupt Withdrawal of Chronic Beta-Blockade: Adaptive Changes in Cyclic AMP and Contractility. J Mol Cell Cardiol. 1981 Nov;13(11):999-1009.

CAS Number: 1189649-47-5

Molecular Weight: 308.85

Compound Purity: 98.25

Research Area: Cardiovascular Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Adrenergic Receptor

• SKU: MEXHY-B1486S-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B1486S-5
• Package Unit: 5 mg
• Quantity Unit: STK