p,p'-DDE-13C12, CAS 201612-50-2

Product Description: p,p'-DDE-13C12 is 13C labeled p,p'-DDE. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C2 13C12H8Cl4

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Kelce WR, et al. Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist. Nature. 1995;375(6532):581-585.

CAS Number: 201612-50-2

Molecular Weight: 329.94

Research Area: Endocrinology

Target: Androgen Receptor;Drug Metabolite;Isotope-Labeled Compounds

• SKU: MEXHY-W753141-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W753141-0
• Package Unit: Get quote
• Quantity Unit: STK