p,p'-DDE-d8, CAS 93952-19-3

Product Description: p,p'-DDE-d8 is the deuterium labeled p,p'-DDE[1]. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM[2].

Formula: C14D8Cl4

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Kelce WR, et al. Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist. Nature. 1995;375(6532):581-585.

CAS Number: 93952-19-3

Molecular Weight: 326.07

Research Area: Endocrinology

Solubility: 10 mM in DMSO

Target: Androgen Receptor;Drug Metabolite

• SKU: MEXHY-B1986S-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B1986S-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK