Product Description: Paroxetine-d6-1 is a deuterated labeled Paroxetine[1]. Paroxetine, a phenylpiperidine derivative, is a potent and selective serotonin reuptake inhibitor (SSRI). Paroxetine is a very weak inhibitor of norepinephrine (NE) uptake but it is still more potent at this site than the other SSRIs[2].
Formula: C19H14D6FNO3
References: [1]M Bourin, et al. Paroxetine: a review. CNS Drug Rev. Spring 2001;7(1):25-47/[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
CAS Number: 1435728-63-4
Molecular Weight: 335.40
Research Area: Neurological Disease
Target: Adrenergic Receptor;Isotope-Labeled Compounds;Serotonin Transporter