Product Description: Pemafibrate-d4 is deuterated labeled 2-Phenylacetaldehyde. 2-Phenylacetaldehyde is an endogenous metabolite.
Applications: COVID-19-anti-virus
Formula: C28H26D4N2O6
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Yamazaki Y, et al. Design and synthesis of highly potent and selective human peroxisome proliferator-activated receptor alpha agonists. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4689-93. Epub2007 May 24./[3]Honda Y, et al. Pemafibrate, a novel selective peroxisome proliferator-activated receptor alpha modulator, improves the pathogenesis in a rodent model of nonalcoholic steatohepatitis. Sci Rep. 2017 Feb 14;7:42477./[4]Sairyo M, et al. A Novel Selective PPARα Modulator (SPPARMα), K-877 (Pemafibrate), Attenuates Postprandial Hypertriglyceridemia in Mice. J Atheroscler Thromb. 2018 Feb 1;25(2):142-152.
CAS Number: 2924193-31-5
Molecular Weight: 494.57
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Isotope-Labeled Compounds;PPAR
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