Prednisone-d4

Product Description: Prednisone-d4 is deuterated labeled Prednisone (HY-B0214). Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus[1][2].

Applications: Metabolism-sugar/lipid metabolism

Formula: C21H22D4O5

References: [1]Qianqian Li, et al. Metabolic Profiling Reveals an Abnormal Pattern of Serum Fatty Acids in MRL/lpr Mice Under Treatment With Prednisone. Front Pharmacol. 2020 Feb 25;11:115./[2]RIEMER AD. Application of the newer corticosteroids to augment diuresis in congestive heart failure. Am J Cardiol. 1958 Apr;1(4):488-96./[3][2]N Tomioka, et al. Effects of prednisolone on acute viral myocarditis in mice. J Am Coll Cardiol. 1986 Apr;7(4):868-72./[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 362.45

Research Area: Cancer; Endocrinology; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Apoptosis;Glucocorticoid Receptor;Isotope-Labeled Compounds

• SKU: MEXHY-B0214S2-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B0214S2-0
• Package Unit: Get quote
• Quantity Unit: STK