Product Description: Protriptyline (N-methyl-d3) (hydrochloride) is the deuterium labeled Protriptyline hydrochloride. Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Unique among the TCAs, protriptyline tends to be energizing instead of sedating, used for narcolepsy to achieve a wakefulness-promoting effect[1].
Applications: Neuroscience-Neuromodulation
Formula: C19H19D3ClN
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Hudgel DW. Pharmacologic treatment of obstructive sleep apnea. J Lab Clin Med. 1995;126(1):13-18.
CAS Number: 1435934-21-6
Molecular Weight: 266.40
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Cholinesterase (ChE);Isotope-Labeled Compounds